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KMID : 0980720080270010069
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Keimyung Medical Journal
2008 Volume.27 No. 1 p.69 ~ p.73
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Abrupt Onset Sheehan’s Syndrome with Acute Adrenal Insufficiency after Delivery
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Kim Yun-Jung
Kim Hye-Sun
Park Keun-Gyu
Kim Mi-Kyung
Jang Young-Yun
Kim Nam-Keong
Hah Yu-Jin
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Abstract
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Sheehan’s syndrome is a postpartum hypopituitarism due to acute ischemic necrosis of the anterior pituitary gland secondary to severe postpartum bleeding and shock. Generally, it is diagnosed several months to years after the last delivery complicated with severe postpartum bleeding. However, we experienced a case of abrupt onset Sheehan’s syndrome with acute adrenal insufficiency occurring 20 days after delivery with severe bleeding. Hormonal study
revealed decreased cortisol and growth hormone response to insulin-induced hypoglycemia. The patient recovered dramatically with glucocorticoid replacement therapy.
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KEYWORD
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Acute Adrenal Insufficiency, Sheehan’s Syndrome
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